Personally I'm not as bothered by it as some may be.
True there are things to be concerned with, regarding this type of subject. Most of which stemming from movies, shows, and other sorts of fictional sources.
A majority of which showcasing the creation of some super monster or monsters that go about massive amounts of slaughter to probable world domination/apocalypse.
But while works of fiction like to play on such things being "evil" or "misguided". there is undoubtedly potential benefits too reap.
An it's due to these benefits, that groups will continue to strive in working out these sorts of experiments, regardless what we think or say.
As for containment and control?
Well aside from the afore mentioned "evil" and "misguided" POV's in fiction, there's also the fact that most fiction likes to make people look like bumbling morons when it comes to containment and control, a factor that usually results in the again afore mentioned mass slaughter an domination/apocalypse. But in real life, while we can't be entirely knowledgeable about every aspect, I'm sure that any possible means of control an containment is taken into account.
Now is or would that be good enough?
It's always been to my understanding that experiments of any kind, are a "gamble", and so not everything goes as planned or hoped for.
As well there'll be cases where it might go beyond expected/predicted results.
So even with the best available in way of containment and control, we do have to take into account the possibility that it might not be enough, and something can happen. That or probable human error.
But the real question would be, with all that in mind. Is it worth the risk?
To which, for me, I'd say ... yeah it might be.