I'm sorry I only read the manga and I wasn't able to watch the anime.
Is there really a difference between the two with regards to plot and how is the ending different? o.o
The anime left out a few plot details that didn't change the overall story from the manga, but after Satoru woke up from his coma in the anime, it strayed away from the manga. Instead of Airi stopping those photographers from taking incriminating pictures of Satoru with Kumi, it was Yashiro, who started befriending amnesic Satoru. Some time later Yashiro planned to murder Kumi and frame Satoru for it, and took Satoru up to the roof of the hospital they were staying in to push the wheelchair-bound Satoru off the roof and make it look like he committed suicide out of guilt from "killing" Kumi.
However, we learn Satoru regained his memories before this murder attempt when he met Kayo again and goads Yashiro into going through with pushing him over the edge of the roof. In the end, Yashiro can't bring himself to do it because waiting for him to return became his reason to live and Satoru filled the hole in his heart, which Satoru was able to predict would be the case. So Satoru pushes himself off the roof anyway and Yashiro tries to prevent it, only for Satoru to safely fall into one of those inflatable stunt air bags, with Kenya and Sawada there having taken a compromising photo of Yashiro "pushing" him off the roof, getting evidence of attempted murder to put him away. We then see Satoru having a reunion with all his childhood friends in Hokkaido, and the final scene is him running into Airi by chance at the same bridge they hid under earlier in the series.
Pettanko FC | To Aru Majutsu no Index FC
"I won't make any excuses for myself. No matter what sins I must bear, I will continue my fight to the end."
Damanos: Well, that's what I mean
Damanos: It's "based" on the stepping on somebody's shadow thing
Damanos: But then Kubo bullshits however he wants beyond that
LoneWolfStark: YYH did that better
Damanos: "YYH did that better"
Damanos: Bleach in a nutshell
-Damanos, September 24, 2015