I don't think Kishi examined the altered chakra angle of the Uchiha's madness enough.
When you look at it as the Uchiha all inheriting a severe mood disorder, then you can understand better why Sasuke would want to murder everyone from his village or Obito could go on a quest for revenge against the world because of something stupid.
If you attribute their behavior to themselves, then it is ridiculous, but we know that strong negative feelings cause the chakra in an Uchiha's brain to change. Which, from a psychological standpoint, is just them becoming unstable because they cannot cope with stressful events.
If you look at Sasuke as a mentally ill person that had to be forced out of a psychotic state because the people in Naruto's age don't have anti-psychotic or mood altering drugs, then you can understand how he can live happily and be accepted in the village now that he is "better"
Really, the way readers regard Sasuke, without giving any consideration to hat Kishi explained as a mental illness, is what you would expect from the characters in the story who live in an age without psychology or mental health resources. On the other hand, the people in the story have accepted Sasuke after his whole revenge episode and allow him to live in their village and work with him. Which is a very tolerated and progressive attitude to have for people in their day and age.
That said, with people like sensor ninja, the Yamanaka clan, and other chakra detection and mind altering jutsu, you'd think Naruto's world would have a good grasp on mental disorders and altered states of mind. Shit, genjutsu is a fighting style that is meant to cause an altered mental state and make people commit foreign actions.